Age-related morphological and anatomical changes were investigated by light and electron microscopy with juvenile and adult leaves of Dendropanax morbifera. Most juvenile leaves were glossy and palmate with five deep and narrow lobes divided nearly to two-thirds of the leaf base. Adult leaves were thick and possessed three lobes divided nearly to half of the leaf base. Stomata were ovoid and found on the abaxial surface. The epicuticular waxes of the plant included platelets, angular rodlets and threads. Platelets were attached to the surface at various angles. Distinct angular rodlets could be found on either the adaxial or the abaxial surface. Platelets on surface undulations occurred exclusively on the abaxial surface of adult leaves. Juvenile leaves were ca. 150 μm thick and had few intercellular spaces. Adult leaves were nearly two times thicker than juvenile leaves, and showed highly vacuolated cells and large intercellular spaces. The cuticle proper was apparent on the epidermis and showed distinctly alternating lamellate structures in juvenile leaves. The epidermal cell wall of adult leaves was covered with a cuticle layer for which a lamellate structure was not found. These results suggest that the species is heteroblastic in leaf characteristics with increasing leaf age.